According
to a new report by STATNews, scientists have implanted human brain
cells into lab rodents, with many of the transplants successful. In one
case, the rodent survived for at least two months, according to the
summaries of the two papers presented at the annual meeting of the
Society for Neuroscience in Washington, D.C.
Four years ago,
scientists in Vienna discovered that human brain tissue could be created
from stem cells. Since then, scientists have been able to make human
brain organoids produce new neurons and develop the six layers of the
human cortex, the region in the brain responsible for advanced cognitive
functions.
The previously unreported experiments are notable
in how the human organoids implanted into mice connected with the
rodent's circulatory system, marking the first-ever brain
vascularization in a rodent. Furthermore, mature neurons from the human
brain organoid sent axons into “multiple regions of the host mouse
brain,” reported by team lead Fred Gage of the Salk Institute.
Although
the extent of the organoid's growth is limited to the tiny confines of
the rodents in the study, the experiment has garnered international
attention, with many questioning the ethics “of whether you are creating
something human-ish that you have to take
seriously in terms of according it dignity and respect — and figuring
out what that even means,” said bioethicist Hank Greely of Stanford
University.
Read more about this fascinating story at: https://www.statnews.com/2017/11/06/human-brain-organoids-ethics/
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Wednesday, November 15, 2017
Science Implant Human Brain 'Organoids' Inside Rats and Mice
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